Solvent-free synthesis of quaternary α-hydroxy α-trifluoromethyl diazenes: the key step of a nucleophilic formylation strategy
نویسندگان
چکیده
منابع مشابه
C6gc00408c 1..9 ++
An efficient, scalable and operationally simple one-pot, 2-step strategy for the nucleophilic formylation of trifluoromethyl ketones is presented. The key step is an unprecedented diaza-carbonyl-ene reaction of formaldehyde tert-butyl hydrazone and trifluoromethyl ketones under solvent-free conditions. This reaction proved to be very fast, clean and high-yielding, affording densely functionalis...
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ژورنال
عنوان ژورنال: Green Chemistry
سال: 2016
ISSN: 1463-9262,1463-9270
DOI: 10.1039/c6gc00408c